Salinomycin Na (55721-31-8) is a polyether ionophore with antibiotic and anti-cancer properties. It induces cell death in some types of cancer cell $ 30.00 – $ 80.00 Select options

Salinomycin (Procoxacin)，一种钾离子载体抗生素，选择性抑制革兰氏阳性菌的生长(gram-positive bacteria)。Salinomycin 是Wnt/β-catenin 信号传导的有效抑制

Salinomycin Na+ ionophores are metabolized in the liver by cytochrome P450 enzymes, and are excreted mostly into bile and feces as parent compound and metabolites in poultry. Following oral administration, residues are present only at very low concentrations in liver and muscle that fall below the limit of decision of the assay within 2 days in poultry. 2019-05-27 Salinomycin, sodium | C42H69NaO11 | CID 23682228 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological Salinomycin, a monocarboxylic ionophore isolated from Streptomyces albus, has been used as an antibiotic [8,9]. Its extensive adoption is due to its high efficacy, spectral properties and positive effects on drug-resistant pathogens. Salinomycin, for example, has been widely used as an anticoccidiosis agent in chickens [10,11].

- Mechanism of Action & Protocol. Salinomycin Na+ ionophores are metabolized in the liver by cytochrome P450 enzymes, and are excreted mostly into bile and feces as parent compound and metabolites in poultry. Following oral administration, residues are present only at very low concentrations in liver and muscle that fall below the limit of decision of the assay within 2 days in poultry. Salinomycin (Procoxacin) is an antibacterial and coccidiostat ionophore therapeutic agent.

Salinomycin is a membrane ionophore, which shows affinity for alkali ions, preferentially for potassium ions. 2 Salinomycin eases the ion flux through cytoplasmic membrane and the mitochondrial membrane.

Salinomycin, traditionally used as an anti-coccidial drug, has recently been shown to possess anti-cancer and anti-cancer stem cell (CSC) effects, as well as activities to overcome multi-drug resistance based on studies using human cancer cell lines, xenograft mice, and in case reports involving cancer patients in pilot clinical trials. Salinomycin (71; R = H), obtained by culturing a strain of Streptomyces albus 〈72JAP(K)7225392〉, and narasin (71; R = Me), 4-(S)-methylsalinomycin, the main component of a polyether complex produced by Streptomyces aurofaciens 〈78JAN1〉 are now used to prevent coccidiosis, particularly in broiler chickens. Salinomycin reduces the proportion of cancer stem cells(CSC) by >100-fold relative to paclitaxel, a commonly used breast cancer chemotherapeutic drug. Millipore Substance identity Substance identity.

Type A medicated articles containing 30 or 60 grams of salinomycin activity per pound (as salinomycin sodium biomass).

2019-05-27 · Salinomycin is a powerful cancer treatment. It is an antibiotic that’s been used to treat infections in poultry, but despite its demonstrated ability to cure human diseases like cancer and malaria, it is rarely used in humans because it would negate the need for conventional treatments like chemotherapy, radiation, and surgery. Salinomycin är ett antibiotikum som vanligtvis används för att förhindra infektioner inom fågelindustrin. Genom att använda salinomycin mot cancerceller som odlas i hypoxi hoppas jag se en större effekt på cancerstamceller eftersom hypoxi leder till fler stamcellsliknande egenskaper.

Salinomycin Accession Number DB11544 Description Not Available Type Small Molecule Groups Vet approved Structure. Download . MOL SDF PDB SMILES InChI. Similar Structures. Structure for Salinomycin (DB11544) Salinomycin(Procoxacin) is an antibacterial and coccidiostat ionophore therapeutic drug.; IC50 Value:; Target: Antibacterial; Anticancer; Salinomycin, a polyether ionophore antibiotic isolated from Streptomyces albus, has been shown to kill CSCs in different types of human cancers, The salinomycin come in different sizes, packaging styles, and designs to address the various concerns of individuals and groups. If you are a farmer with many animals, you will find salinomycin in large packages to provide you with optimal transportation convenience. Visit ChemicalBook To find more Salinomycin(53003-10-4) information like chemical properties,Structure,melting point,boiling point,density,molecular formula,molecular weight, physical properties,toxicity information,customs codes.
Fiske kvoter

SALINOMYCIN SODIUM. Salinomycin sodium salt. Salinomycin (sodium salt) UNII-92UOD3BMEK. 55721-31-8 Type A medicated articles containing 30 or 60 grams of salinomycin activity per pound (as salinomycin sodium biomass). Salinomycin is a membrane ionophore, which shows affinity for alkali ions, preferentially for potassium ions.

2011-06-02 · Salinomycin is a polyether antibiotic with properties of an ionophore, which is commonly used as cocciodiostatic drug and has been shown to be highly effective in the elimination of cancer stem Salinomycin sodium, Sodium salinomycin: SMILES: CCC(C1CCC(C(O1)C(C)C(C(C)C(=O)C(CC)C2C(CC(C3(O2)C=CC(C4(O3)CCC(O4)(C)C5CCC(C(O5)C)(CC)O)O)C)C)O)C)C(=O)O.[Na+] Storage: Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of Översättnings-API; Om MyMemory; Logga in Salinomycin analogs: Mechanistic probes and structure–activity relationships against cancer stem cells. Forskningsoutput: Avhandling › Doktorsavhandling (sammanläggning) 2019-11-25 · Salinomycin is administered to cancer patients via intravenous injection.
Omexamination

Salinomycin sodium salt. Catalog # 3637. Datasheet / COA / SDS. Antibiotics Small Molecule. Discontinued Product. 3637 has been discontinued. View all

Salinomycin is used to control coccidia in animals and for growth promotion in ruminants. Salinomycin sodium (SAL‐Na) is active against certain Gram‐positive bacteria, while Gram‐negative species are resistant. SAL‐Na at the proposed concentration is unlikely to increase shedding of Salmonella, Escherichia coli and Campylobacter and or induce resistance and cross‐resistance to antimicrobials important in human and animal Unfortunately Salinomycin sodium salt (Cat.